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宫颈癌MRI:50例宫颈癌术前MRI确诊与分期

点击:0时间:2018-10-13 16:52:23

刘红宇+++++生启芳++++裘华敏++++杨文海++++应申鹏

[摘要] 意图 剖析宫颈癌的MRI体现,点评MRI对宫颈癌术前确诊与分期的价值。办法 收集本院2009年1月~2013年1月50例经病理证明的宫颈癌患者的临床材料和MRI材料。年纪32~75岁,均匀45岁。首要临床症状为阴道不规则流血,包含触摸性、性交后和绝经后。病理确诊:鳞癌42例,腺癌6例,腺鳞癌2例。50例患者中21例行手术医治,其他行放疗。回忆性剖析其MRI印象特征,调查肿瘤的方位、巨细、信号特征以及对周围安排的侵略状况。成果 宫颈癌MRI体现:T1WI呈低或等信号,T2WI呈高信号,与正常宫颈基质(低信号)及宫旁脂肪(高信号)构成杰出的比照,GD-DTPA增强呈轻度均匀或不均匀强化。一起显现宫体、宫旁、阴道、盆壁、器官侵略及淋巴结搬运等。 定论 MRI显现宫颈癌瘤灶、侵略规模与途径,显着优于其他印象学查看,对发现宫旁侵略状况显着优于临床,应作为宫颈癌术前惯例的印象学查看办法。

[关键词] 子宫颈癌;磁共振成像;肿瘤分期

[中图分类号] R737.33[文献标识码] B[文章编号] 1673-9701(2014)15-0047-03

MRI for diagnosis and staging of cervical cancer before surgery

LIU Hongyu1 SHENG Qifang2 QIU Huamin1 YANG Wenhai3 YING Shenpeng1

1.Department of Radiology, Taizhou City Center Hospital in Zhejiang Province, Taizhou 318000,China; 2.Ningbo City Yinzhou District the Second Hospital,Ningbo 315192,China;3.Department of Radiology, the First People's Hospital of Taizhou in Zhejiang Province, Taizhou 318020,China

[Abstract] Objective To analyze the value of MRI evaluation diagnosis and staging for cervical cancer. Methods Anarzed the clihical data and MRI of 50 cases pathologically confirmed cervical cancer patients. Aged 32-75 years,mean age 45 years. The main clinical symptom of irregular vaginal bleeding,included post-contact,sexual intercourse,and after menopause. Pathological diagnosis of squamous cell carcinoma in 42 cases,six cases of adenocarcinoma, adenosquamous carcinoma in 2 cases. 21 of 50 patients underwent surgical treatment,and the remaining radiotherapy.retrospectively analyzed MRI features observed tumor location,size, signal characteristics as well as violations of the surrounding tissue. Results Cervical MRI showed:T1WI showed low or equal signal, T2WI showed high signal, with normal cervical stromal(low signal) and parametrial fat(high signal) to form a good natural contrast, GD-DTPA enhancement showed mild degree homogeneous or inhomogeneous enhancement. Also showed palace,uterine,vaginal,pelvic wall,organ invasion and lymph node metastasis. Conclusion MRI of cervical tumor foci display violated the scope and ways, superior to other imaging studies,the discovery of parametrial invasion is significantly better than the clinical situation,as a former cancer eheck methods should be routine imaging methods.

[Key words] Cervical cancer ; Magnetic resonance imaging ; Tumor stage宫颈癌是女人生殖器最常见的恶性肿瘤之一,术前能否前期确诊与精确分期直接关系着医治计划和预后[1]。临床确诊是经过专科查看或细胞学查看,而难以确定肿瘤的侵略途径和规模。有研讨标明磁共振成像(Magnetic Resonance Imaging,MRI)在宫颈癌的确诊和分期中有着很重要的位置,是现在子宫颈癌宫旁侵略及周围器官搬运的最佳的无创性查看办法,在子宫颈癌分期上的价值显着优于超声和CT,但现在关于MRI确诊宫颈癌及其分期的精确率却报导纷歧[2]。本研讨对该院2009年1月~2013年1月收集的50例经病理证明的宫颈癌患者的临床材料和MRI材料进行回忆性剖析,旨在讨论MRI在宫颈癌术前确诊和分期中的使用价值,现报导如下。

1 材料与办法

1.1 临床材料

收集本院2009年1月~2013年1月50例经病理证明的宫颈癌患者的临床材料和MRI材料,均具有完好具体的手术记载和病理记载,年纪规模32~75岁,均匀年纪45岁。首要临床症状为阴道不规则流血,包含触摸性、性交后和绝经后。病理确诊为鳞癌42例,腺癌6例,腺鳞癌2例。50例患者中21例行手术医治,其他行放疗。

1.2 仪器与办法

MR查看选用GE Signa HDxt 1.5T超导磁共振扫描仪。MR查看序列包含:AX T1WI FSE序列,TR 467 ms,TE 7.5 ms;AX T2WI FSE序列,TR 2250 ms,TE 95 ms;SAG T2WI FSE+FS序列,TR 4200 ms,TE 85 ms;COR STIR序列,TR 5000 ms,TE 68 ms;LAVA序列,TR 3.7 ms,TE 1.7 ms;DWI序列 TR 4500 ms,TE 75.1 ms;经肘静脉注射GD-DTPA 0.01 mmol/kg后,行LAVA序列3期扫描。扫描层厚除LAVA序列3 mm,其他均为6 mm。MRI图画均由两名副主任医师别离阅片,依据阅片成果清晰宫颈癌的MRI分期。临床分期由妇产科副主任医师依据FIGO分期分类。宫颈癌的临床分期选用世界妇产科协会(FIGO)分类法 ,该分类法首要是依据阴道、宫旁、盆壁、膀胱及直肠侵略与否进行分期。

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