盐酸曲美他嗪片 曲美他嗪对晚年冠心病心绞痛兼并高血脂患者的效果

宋晨光

[摘要] 意图 讨论曲美他嗪医治晚年冠心病心绞痛兼并高血脂患者的作用。 办法 選择我院从2014年8月～2016年11月间收治的晚年冠心病心绞痛兼并高血脂患者58例作为研讨目标，依照患者入院日期单双号随机分组计划，将其分为两组，分别为对照组和试验组；对照组患者选用硝苯地平缓释片进行医治，而试验组患者在对照组的用药基础上参加曲美他嗪对患者进行医治；比照两组患者的冠心病心绞痛发生情况，点评其医治有效性，一起记载患者的总胆固醇（TC）和甘油三酯（TG）改变，比照两组患者的医治成果。 成果 试验成果显现，试验组患者的冠心病医治总有功率显着优于对照组，组间差异具有统计学含义（P<0.05）。但两组患者医治后血脂情况未获得显着改进，医治前后和两组间比较差异均无统计学含义（P>0.05）。 定论 使用曲美他嗪对冠心病心绞痛进行医治，具有较好的医治作用，但假如使用于晚年冠心病心绞痛兼并高血脂患者的医治时，还需要使用相应的降血脂药物对患者进行医治，才干确保患者的医治作用，然后进步患者的康复情况。

[关键词] 曲美他嗪；冠心病；心绞痛；高血脂

[中图分类号] R541.4 [文献标识码] B [文章编号] 1673-9701（2018）07-0034-03

[Abstract] Objective To investigate the effectiveness of trimetazidine in elder patients with coronary heart disease and angina pectoris combined with hyperlipidemia. Methods 58 patients with coronary heart disease and angina pectoris combined with hyperlipidemia in our hospital from August 2014 and November 2016 were selected and randomized into control group and experimental group according to the odd-even admission date. Patients in control group were treated with nifedipine sustained release tablets. Patients in experimental group were given additional trimetazidine. The attacks of angina pectoris in patients of two groups were compared to evaluate the effectiveness of the treatment. The changes of total cholesterol（TC） and triglyceride（TG） were recorded to compare the treatment outcome. Results It showed the effectiveness of coronary heart disease treatment in experimental group was significantly better than that in control group（P<0.05）. The levels of blood cholesterol after treatment were not improved significantly in both of two groups compared with the levels before treatment， nor were significant difference found between two groups（P>0.05）. Conclusion The effectiveness of trimetazidine in patients with coronary heart disease and angina pectoris is good. However， it is necessary to combine cholesterol-lowering drugs with trimetazidine in the treatment of elder patients with coronary heart disease and angina pectoris combined with hyperlipidemia to assure the effectiveness and improve the recovery of patients.

[Key words] Trimetazidine； Coronary heart disease； Angina pectoris； Hyperlipidemia

冠心病是临床常见的一种心脏病，多是由于患者心肌内呈现缺血缺氧或许心肌坏死的情况所发生[1]。而高血脂则是跟着人们日子质量的不断提高，饮食不规则或许作息不规则所发生的一种疾病，临床发生率相对较高，对患者影响较大，在部分情况下，假如未对其进行及时操控，还会引发大脑心脏肾脏等安排呈现系列并发症，严重威胁患者生命安全[2]。且依据当时的临床材料显现，高血脂患者的数量有显着增加的趋势。而高血脂的存在有或许诱发冠心病，冠心病的存在多会引发高血脂，故而临床将高血脂与冠心病相互视为风险要素[3]。冠心病兼并高血脂患者的医治难度较大，且预后欠安，严重危害患者生命安全[4]。因而临床关于其用药与护理均相对注重。曲美他嗪是常用的医治冠心病的药物，其作用相对较好。本次研讨中挑选我院从2014年8月～2016年11月间收治的晚年冠心病心绞痛兼并高血脂患者58例作为研讨目标，讨论曲美他嗪用于晚年冠心病心绞痛兼并高血脂患者的医治作用。